Certara.NLME8: Utilities for Certara's Nonlinear Mixed-Effects Modeling Engine
Interface to Certara's Nonlinear Mixed-Effects (NLME) modeling
engine ('NLME-Engine') for pharmacokinetic and pharmacodynamic (PK/PD)
modeling and simulation. Provides access to the Maximum Likelihood
estimation algorithms available in the 'Phoenix' NLME platform for
population, individual, and pooled analyses using parametric methods.
Includes utilities for setting up NLME installations and
parallel settings, running estimation, bootstrap, and covariate search
workflows, and updating model files from engine output. Jobs can be
executed locally or across high-performance computing resources,
including Linux Sun Grid Engine (SGE) and Simple Linux Utility for
Resource Management (SLURM) grids as well as multicore Linux and
Windows hosts.
| Version: |
3.2.0 |
| Depends: |
R (≥ 4.0.0) |
| Imports: |
xml2, batchtools (≥ 0.9.9), utils, data.table |
| Suggests: |
testthat, brew, withr |
| Published: |
2026-09-11 |
| DOI: |
10.32614/CRAN.package.Certara.NLME8 |
| Author: |
Soltanshahi Fred [aut],
Michael Tomashevskiy [aut],
James Craig [aut, cre],
Shuhua Hu [ctb],
Certara USA, Inc. [cph, fnd] |
| Maintainer: |
James Craig <james.craig at certara.com> |
| License: |
LGPL-3 |
| NeedsCompilation: |
no |
| Materials: |
README |
| CRAN checks: |
Certara.NLME8 results |
Documentation:
Downloads:
Reverse dependencies:
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