Package: tcplfit2
Title: A Concentration-Response Modeling Utility
Version: 0.1.9
Authors@R: c(person("Thomas", "Sheffield", role = c("aut")),
				person("Jason", "Brown", role = "ctb", email = "brown.jason@epa.gov", comment = c(ORCID = "0009-0000-2294-641X")),
				person("Sarah E.","Davidson-Fritz",role=c("ctb"),email="davidsonfritz.sarah@epa.gov", comment = c(ORCID = "0000-0002-2891-9380")),
				person("Madison","Feshuk",role = c("ctb","cre"),email = "feshuk.madison@epa.gov", comment = c(ORCID = "0000-0002-1390-6405")),
				person("Lindsay","Knupp",role=c("ctb"),email = "knupp.lindsay@epa.gov"),
				person("Zhihui","Zhao",role=c("ctb")),
				person("Richard S", "Judson", role = c("ctb"), comment = c(ORCID = "0000-0002-2348-9633")),
				person("Katie", "Paul Friedman", role=c("ctb"), email = "paul-friedman.katie@epa.gov", comment = c(ORCID = "0000-0002-2710-1691"))
			)
Description: The tcplfit2 R package performs basic concentration-response curve fitting. The original tcplFit() function in the tcpl R package performed basic concentration-response curvefitting to 3 models. With tcplfit2, the core tcpl concentration-response functionality has been expanded to process diverse high-throughput screen (HTS) data generated at the US Environmental Protection Agency, including targeted ToxCast, high-throughput transcriptomics (HTTr) and high-throughput phenotypic profiling (HTPP). tcplfit2 can be used independently to support analysis for diverse chemical screening efforts.
URL: https://github.com/USEPA/CompTox-ToxCast-tcplFit2
License: MIT + file LICENSE
Encoding: UTF-8
LazyData: true
RoxygenNote: 7.3.2
Suggests: knitr, rmarkdown, stringi, DT, data.table, tcpl, prettydoc,
        testthat (>= 3.0.0), here, htmlTable, tidyr, dplyr, gridExtra,
        rmdformats
VignetteBuilder: knitr
Imports: stats, methods, numDeriv, RColorBrewer, stringr, reshape2,
        ggplot2 (>= 3.5.0)
Depends: R (>= 3.5.0)
Config/testthat/edition: 3
BugReports: https://github.com/USEPA/CompTox-ToxCast-tcplFit2/issues
NeedsCompilation: no
Packaged: 2025-07-23 14:03:04 UTC; MFeshuk
Author: Thomas Sheffield [aut],
  Jason Brown [ctb] (ORCID: <https://orcid.org/0009-0000-2294-641X>),
  Sarah E. Davidson-Fritz [ctb] (ORCID:
    <https://orcid.org/0000-0002-2891-9380>),
  Madison Feshuk [ctb, cre] (ORCID:
    <https://orcid.org/0000-0002-1390-6405>),
  Lindsay Knupp [ctb],
  Zhihui Zhao [ctb],
  Richard S Judson [ctb] (ORCID: <https://orcid.org/0000-0002-2348-9633>),
  Katie Paul Friedman [ctb] (ORCID:
    <https://orcid.org/0000-0002-2710-1691>)
Maintainer: Madison Feshuk <feshuk.madison@epa.gov>
Repository: CRAN
Date/Publication: 2025-07-23 15:20:02 UTC
Built: R 4.7.0; ; 2026-06-21 03:38:57 UTC; windows
