Package: factorial2x2
Type: Package
Title: Design and Analysis of a 2x2 Factorial Trial
Version: 0.2.0
Author: Eric Leifer and James Troendle   
Maintainer: Eric Leifer <Eric.Leifer@gmail.com>
Description: Used for the design and analysis of a 2x2 factorial trial for
    a time-to-event endpoint.  It performs power calculations and significance
    testing as well as providing estimates of the relevant hazard ratios and the 
    corresponding 95% confidence intervals.  Important reference papers include
    Slud EV. (1994) <https://www.ncbi.nlm.nih.gov/pubmed/8086609>
    Lin DY, Gong J, Gallo P, Bunn PH, Couper D. (2016) <DOI:10.1111/biom.12507>
    Leifer ES, Troendle JF, Kolecki A, Follmann DA. (2020)
    <https://github.com/EricSLeifer/factorial2x2/blob/master/Leifer%20et%20al.%20paper.pdf>.
Depends: R (>= 3.6.0), survival, stats, mvtnorm
Imports:
License: GPL-2
Encoding: UTF-8
LazyData: true
Suggests: knitr, rmarkdown
VignetteBuilder: knitr
RoxygenNote: 7.1.0
NeedsCompilation: no
Packaged: 2020-04-27 15:12:19 UTC; leifere
Repository: CRAN
Date/Publication: 2020-04-27 15:40:02 UTC
Built: R 4.6.0; ; 2025-07-18 06:04:55 UTC; unix
